Establishing a Single Source of Truth (SSOT) is essential for organizational efficiency, ensuring data integrity and informed decision-making. This guide outlines the importance of SSOT and key implementation steps, including identifying critical data elements, selecting suitable technology, establishing governance, securing stakeholder buy-in, and embracing continuous improvement. Illustrated through a case study of LNNRT, SSOT's transformative impact is evident, highlighting its role in maximizing data value and driving sustainable growth.